11 research outputs found

    Use of ensemble based on GA for imbalance problem

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    In real-world applications, it has been observed that class imbalance (significant differences in class prior probabilities) may produce an important deterioration of the classifier performance, in particular with patterns belonging to the less represented classes. One method to tackle this problem consists to resample the original training set, either by over-sampling the minority class and/or under-sampling the majority class. In this paper, we propose two ensemble models (using a modular neural network and the nearest neighbor rule) trained on datasets under-sampled with genetic algorithms. Experiments with real datasets demonstrate the effectiveness of the methodology here propose

    Overlap versus Imbalance

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    Learning with Class Skews and Small Disjuncts

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    Ab initio insights into the structural, energetic, electronic, and stability properties of mixed CenZr15- nO30 nanoclusters

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    Mixed CeO-ZrO nanoclusters have the potential to play a crucial role in nanocatalysis, however, the atomistic understanding of those nanoclusters is far from satisfactory. In this work, we report a density functional theory investigation combined with Spearman rank correlation analysis of the energetic, structural and electronic properties of mixed CeZrO nanoclusters as a function of the composition (n = 0, 1,...,14, 15). For instance, we found a negative excess energy for all putative global minimum CeZrO configurations with a minimum at about n = 6 (i.e., nearly 40% Ce), in which both the oxygen anion surroundings and cation radii play a crucial role in the stability and distribution of the chemical species. We found a strong energetic preference of Zr cations to occupy larger coordination number sites, i.e., the nanocluster core region, while the Ce cations are located near vacuum exposed O-rich regions. As expected, we obtained an almost linear decrease of the average bond lengths by replacing Ce by Zr cations in the (ZrO) nanoclusters towards the formation of mixed CeZrO nanoclusters, which resulted in a shift towards higher vibrational frequencies. Besides, we also observed that the relative stability of the mixed oxides is directly correlated with the increase (decrease) of the Zr d-state (Ce f-state) contribution to the highest occupied molecular orbital with the increase of the Zr content, hence driving the gap energy towards higher values.The authors gratefully acknowledge support from FAPESP (São Paulo Research Foundation, Grant Number 2017/11631-2, 2018/11152-0), Shell and the strategic importance of the support given by ANP (Brazil's National Oil, Natural Gas and Biofuels Agency) through the R&D levy regulation. This study was financed in part by the Coordenacão de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES) – Finance Code 001. The authors acknowledge also the National Laboratory for Scientific Computing (LNCC/MCTI, Brazil) for providing HPC resources of the SDumont supercomputer, which have contributed to the research results reported within this paper. URL: http://sdumont.lncc.br. JLFDS acknowledges the Advanced Scientific Computational Laboratory (University of São Paulo) and the infrastructure provided to our computer cluster by the São Carlos Center of Informatics, University of São Paulo

    Resampling methods versus cost functions for training an MLP in the class imbalance context

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    The class imbalance problem has been studied from different approaches, some of the most popular are based on resizing the data set or internally basing the discrimination-based process. Both methods try to compensate the class imbalance distribution, however, it is necessary to consider the effect that each method produces in the training process of the Multilayer Perceptron (MLP). The experimental results shows the negative and positive effects that each of these approaches has on the MLP behavio

    Risk management of HBsAg or anti-HCV positive healthcare workers in hospital

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    Recommendations are made for controlling the transmission of the hepatitis B and hepatitis C viruses from healthcare workers to patients. These recommendations were based both on the literature and on experts' opinions, obtained during a Consensus Conference. The quality of the published information and of the experts' opinions was classified into 6 levels, based on the source of the information. The recommendations can be summarised as follows: all healthcare workers must undergo hepatitis B virus vaccination and adopt the standard measures for infection control in hospitals; healthcare workers who directly perform invasive procedures must undergo serological testing and the evaluation of markers of viral infection. Those found to be positive for: 1) HBsAg and HBeAg, 2) HBsAg and hepatitis B virus DNA, or 3) anti-hepatitis C virus and hepatitis C virus RNA must abstain from directly performing invasive procedures; no other limitations in their activities are necessary. Infected healthcare workers are urged to inform their patients of their infectious status, although this is left to the discretion of the healthcare worker; whose privacy is guaranteed by law. If exposure to hepatitis B virus occurs, the healthcare worker must undergo prophylaxis with specific immunoglobulins, in addition to vaccination

    A Systematic Review on Donepezil-based Derivatives as Potential Cholinesterase Inhibitors for Alzheimer’s Disease

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    Therapeutic Strategies Targeting Amyloid-β in Alzheimer’s Disease

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